LymphedemaV1, Main, Exploration, bibRecord, 003367

Nanopharmaceuticals to target antifilarials: a comprehensive review.

Identifieur interne : 003367 ( Main/Exploration ); précédent : 003366; suivant : 003368

Nanopharmaceuticals to target antifilarials: a comprehensive review.

Auteurs : Mohammad Ali [Inde] ; Mohammad Afzal ; Shailja Misra Bhattacharya ; Farhan Jalees Ahmad ; Amit Kumar Dinda

Source :

Expert opinion on drug delivery [ 1744-7593 ] ; 2013.

RBID : pubmed:23427945

Descripteurs français

KwdFr :
- Animaux, Chimie pharmaceutique, Filaricides (administration et posologie), Filarioidea (), Filariose lymphatique (traitement médicamenteux), Humains, Liposomes (), Nanoparticules (), Systèmes de délivrance de médicaments, Wolbachia ().
MESH :
- administration et posologie : Filaricides.
- traitement médicamenteux : Filariose lymphatique.
- Animaux, Chimie pharmaceutique, Filarioidea, Humains, Liposomes, Nanoparticules, Systèmes de délivrance de médicaments, Wolbachia.

English descriptors

KwdEn :
- Animals, Chemistry, Pharmaceutical, Drug Delivery Systems, Elephantiasis, Filarial (drug therapy), Filaricides (administration & dosage), Filarioidea (drug effects), Humans, Liposomes (chemistry), Nanoparticles (chemistry), Wolbachia (drug effects).
MESH :
- chemical , administration & dosage : Filaricides.
- chemical , chemistry : Liposomes.
- chemistry : Nanoparticles.
- drug effects : Filarioidea, Wolbachia.
- drug therapy : Elephantiasis, Filarial.
- Animals, Chemistry, Pharmaceutical, Drug Delivery Systems, Humans.

Abstract

Currently emphasized conventional chemotherapies for the elimination of lymphatic filariasis (LF) are imperfect due to unfocused targeting of poorly water-soluble antifilarial drugs. The profound location of drug targets (filarial parasites or wolbachia) within the complex anatomy of lymphatic tissues often necessitates prolonged treatment schedules with high doses leading to undesired side effects and poor patient compliance. Therefore, we need to reformulate antifilarial drugs taking the advantages of nanotechnology through a wide range of nanomedical carriers, which improve drug efficacy, increase bioavailability, and diminish toxicity.

DOI: 10.1517/17425247.2013.771630
PubMed: 23427945

Affiliations:

Inde

Le document en format XML

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<front><div type="abstract" xml:lang="en">Currently emphasized conventional chemotherapies for the elimination of lymphatic filariasis (LF) are imperfect due to unfocused targeting of poorly water-soluble antifilarial drugs. The profound location of drug targets (filarial parasites or wolbachia) within the complex anatomy of lymphatic tissues often necessitates prolonged treatment schedules with high doses leading to undesired side effects and poor patient compliance. Therefore, we need to reformulate antifilarial drugs taking the advantages of nanotechnology through a wide range of nanomedical carriers, which improve drug efficacy, increase bioavailability, and diminish toxicity.</div>
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Serveur d'exploration sur le lymphœdème

Nanopharmaceuticals to target antifilarials: a comprehensive review.

Nanopharmaceuticals to target antifilarials: a comprehensive review.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

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